Hand Holding Olumiant 1 daily pill

1 daily pill

Olumiant is a once-daily pill for adults with moderately to severely active RA for whom a TNF inhibitor did not work well enough.

Quick relief in signs and symptoms

In a study, some people taking Olumiant experienced a 20% improvement in the signs and symptoms of their RA as early as 7 days. Others saw improvement at 12 weeks.

Need some helpful tips on talking with your doctor?

Relief as early as 1 week
1 daily pill

If you've struggled with RA in the past, Olumiant may be able to help

If you have tried a TNF inhibitor for RA and haven't noticed enough improvement in your symptoms, Olumiant may be an effective option.

Ease of use

The pill, bottle, and cap were designed with RA patients in mind.

Arthritis Foundation’s Ease-of-Use Commendation awarded to Olumiant’s medicine bottle features

These features have been awarded the Arthritis Foundation's Ease-of-Use Commendation.*

*The Arthritis Foundation's Ease-of-Use Commendation recognizes products tested to help make daily tasks easier for people who have arthritis and other physical limitations.

RA patient opening easy-to-use Olumiant medicine bottle
Someone asking How do I take Olumiant?

How do I take Olumiant?

Olumiant is a once-daily RA treatment available as a 2 mg pill. It’s important to note:

  • Olumiant is not an injection
  • It should be taken exactly as prescribed
  • It can be taken with or without food

Most common side effects

When taking Olumiant, you may experience any of the following common side effects:

  • Upper respiratory tract infections (such as a cold or sinus infection)
  • Nausea
  • Cold sores
  • Shingles

There may be other side effects when taking Olumiant.

Side Effects
Talk with your doctor

Tips for talking with your doctor

Consider asking your doctor the following questions to help you gain a better understanding of Olumiant:

  • How does Olumiant work?
  • What is the most important safety information I should know about Olumiant?
  • How might Olumiant help my RA?
  • How do I take Olumiant and how often do I take it?
PURPOSE and SAFETY SUMMARY Warning: Serious Infections, Cancers and Blood Clots
Warning: Serious Infections, Cancers and Blood Clots
PURPOSE AND SAFETY SUMMARY

Important Facts About Olumiant® (O-loo-mē·ant). It is also known as baricitinib.

Olumiant is a prescription medicine used to treat adults with moderately to severely active rheumatoid arthritis (RA) who have tried at least one other medicine called a tumor necrosis factor (TNF) antagonist that did not work well enough or could not be tolerated. The medicine comes in a tablet and is taken orally.

WARNINGS
Olumiant may cause serious side effects. Some people who have taken Olumiant have had:
  • Serious infections, including tuberculosis (TB), shingles, and others caused by bacteria, fungi, or viruses. Some people have died from these infections. Olumiant can make you more likely to get infections or make them worse. Your doctor should test for TB before starting Olumiant and watch for TB symptoms during treatment. You should not start Olumiant if you have any kind of infection unless your doctor tells you it is okay. While taking Olumiant, tell your doctor right away if you have symptoms of an infection, such as:

    • fever, sweating, or chills
    • muscle aches
    • cough
    • shortness of breath
    • blood in phlegm
    • weight loss
    • warm, red, or painful skin or sores on your body
    • diarrhea or stomach pain
    • burning with urination or urinating more often than normal
    • feeling tired
  • Cancer and immune system problems. Olumiant may increase your risk of lymphoma and other cancers, including skin cancers.
  • Blood clots in the veins of your legs or lungs. This may be life-threatening and cause death. While taking Olumiant, tell your doctor right away if you have any signs and symptoms of blood clots, including swelling, pain or tenderness in the leg, sudden chest pain, or shortness of breath.
  • Tears in the stomach or intestines. This happens most often in people who also take nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, or methotrexate. While taking Olumiant, tell your doctor right away if you have fever and stomach-area pain that does not go away, and a change in bowel habits.
  • Changes in laboratory test results. Your doctor should do blood tests to check your white and red blood cells before and while you are taking Olumiant. Your doctor should also check certain liver tests. You should not take Olumiant if your blood cell counts are too low or your liver tests are too high. If your results change, your doctor may pause your treatment with Olumiant. Your doctor should also check your cholesterol approximately 12 weeks after you start this medicine and as needed after that.
COMMON SIDE EFFECTS

The most common side effects of Olumiant include:

  • upper respiratory tract infections, such as a cold or sinus infections
  • nausea
  • cold sores
  • shingles

These are not all the possible side effects of Olumiant. Tell your doctor if you have any side effects. You can report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

BEFORE USING

Before you use Olumiant, tell your doctor if you:

  • Are being treated for an infection, have an infection that won’t go away or keeps coming back, or think you have symptoms of an infection.
  • Have TB or have been in close contact with someone with TB.
  • Have had hepatitis B or C, cancer, or blood clots in the veins of your legs or lungs.
  • Live, have lived, or have visited parts of the country that increase your risk of fungal infections. These may include the Ohio and Mississippi River valleys and the Southwest. Ask your doctor if you do not know if you have lived in an area where these infections are common.
  • Have other medical conditions, including kidney or liver problems, low blood cell counts, diabetes, lung disease, HIV, or a weak immune system.
  • Have any stomach-area pain or have been diagnosed with inflammation in the large intestine or ulcers in your stomach or intestines.
  • Have recently received or plan to receive a vaccine. People taking Olumiant should not receive live vaccines.
  • Are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. You should not take Olumiant and breastfeed.
  • Are taking other medicines, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your doctor, if you take a medicine called probenecid or any other medicines to treat rheumatoid arthritis. For example, you should not take any of the following medicines while taking Olumiant since this may increase your risk of infection:


    • tocilizumab (Actemra®)
    • etanercept (Enbrel®)
    • adalimumab (Humira®)
    • infliximab (Remicade®)
    • rituximab (Rituxan®)
    • abatacept (Orencia®)
    • anakinra (Kineret®)
    • certolizumab pegol (Cimzia®)
    • golimumab (Simponi®)
    • tofacitinib (Xeljanz®/Xeljanz XR®)
    • sarilumab (Kevzara®)
    • azathioprine or cyclosporine
  • Are under age 18. It is not known if Olumiant is safe and effective in children.
HOW TO TAKE
  • Take Olumiant exactly as your doctor says.
  • Take Olumiant once a day with or without food.
LEARN MORE

For more information, call 1-800-545-5979.
This summary provides basic information about Olumiant but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. Be sure to talk to your doctor or other healthcare provider about Olumiant and how to take it. Your doctor is the best person to help you decide if Olumiant is right for you.

Please see full Prescribing Information, including Warnings on Serious Infections, Cancers, and Blood Clots, and Medication Guide.

Olumiant® is a registered trademark owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates. All other product names and trademarks are the property of their respective trademark owners. ©Lilly USA, LLC 2019.

BA CON BS 08JAN2019